Symptoms: Huntington's disease (HD) is a hereditary and progressive brain disorder. You can't "catch" it from another person. Although symptoms may first show up in midlife, Huntington's can strike anyone from childhood to advanced age. Over 10 to 25 years, the disease gradually kills nerve cells in the brain. This affects the body, mind, and emotions. Symptoms can vary greatly from person to person. And stress or excitement can worsen symptoms. Some symptoms are easier to spot than others. Abnormal movements may be the first thing you notice.weight loss can be a concern at all stages. Symptoms of Huntington's disease tend to develop in stages. Early stage. Changes may be quite subtle in early stages, making it possible to keep driving and working. You may just require a little extra help.